ODCs

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2 OMIM references -
1 associated gene
10 signs/symptoms

PROTEIN INTERACTIONS: 3
COMMON SIGNS: 1

1 OMIM reference -
3 associated genes
5 signs/symptoms

Fibronectin glomerulopathy

Familial hypofibrinogenemia


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	FN1 FN1 FN1	(0.63) (0.63) (0.63)	FGA FGB FGG

Citations in the biomedical literature:

Fibronectin glomerulopathy		Familial hypofibrinogenemia
	Synonym(s): - GFND - Glomerulopathy with fibronectin deposits		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare genetic disease - Rare renal disease		Classification (Orphanet): - Rare genetic disease - Rare hematologic disease

	Classification (ICD10): - Diseases of the genitourinary system -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: - Type of inheritance: autosomal dominant

	External references: 2 OMIM references - No MeSH references		External references: 1 OMIM reference - No MeSH references


COMMON SIGNS	- Autosomal dominant inheritance

Fibronectin glomerulopathy		Familial hypofibrinogenemia
	Very frequent - Chronic arterial hypertension - Edema of the legs / lower limbs - Functional anomalies of the kidney and the urinary tract - Hematuria / microhematuria - Nephrotic syndrome - Proteinuria - Renal failure - Renal glomerular defect / glomerulopathy Occasional - Intracranial / cerebral / meningeal hemorrhage		Very frequent - Epistaxis / nose bleeding - Gastrointestinal bleeding / hemorrhage / hematemesis / melena / rectorrhagia - Gingivorrhagia / gingival bleeding - Hemorrhage / hemorrhagic syndrome / excessive / long-lasting bleeding